A method of assessing the quality of pharmaceutical market and industry reports as a source to study access to medicines

This repository item contains a single issue of the Health and Development Discussion Papers, an informal working paper series that began publishing in 2002 by the Boston University Center for Global Health and Development. It is intended to help the Center and individual authors to disseminate work that is being prepared for journal publication or that is not appropriate for journal publication but might still have value to readers.Market and industry reports can be useful in studying access to medicines from a pharmaceutical market perspective. However, many market and industry reports lack some or much of the information required to conduct analyses to study access to medicines and are often not transparent in their data sources and research methodologies. The instrument developed in this study, titled the Pharmaceutical Market and Industry Report Assessment Tool (PIRAT), assesses the quality of pharmaceutical market and industry reports, specifically focusing on the needs of public health researchers, and includes criteria describing the content and quality of the market reports. The assessment tool generates an unweighted score indicating the relative strengths and weaknesses of reports

Depression and Anxiety in Roman Catholic Secular Clergy

A nationally selected random sample of Roman Catholic secular priests was investigated using the Center for Epidemiological Studies-Depression scale and the State-Trait Anxiety Inventory Form Y. Additionally, a Self-Report Inventory requested information regarding participants\u27 demographics as well as four categories of predictor variables (i.e., Vocational Satisfaction, Social Support, Spiritual Activities, Physical Environment) potentially associated with depression and anxiety. The study yielded a return rate of 64%. Secular clergy reported significantly greater depression and anxiety (both state and trait) than are reported in the general population. Low Vocational Satisfaction was found to be predictive of depression as well as both state and trait anxiety. Additionally, low Social Support was found to be predictive of state and trait anxiety. When the significant predictor variables were conceptually collapsed, it appeared that both people and place were significantly related to Roman Catholic secular priests\u27 experience of depression and anxiety

Developing drought resilience in irrigated agriculture in the face of increasing water scarcity

In many countries, drought is the natural hazard that causes the greatest agronomic impacts. After recurrent droughts, farmers typically learn from experience and implement changes in management to reduce their future drought risks and impacts. This paper aims to understand how irrigated agriculture in a humid climate has been affected by past droughts and how different actors have adapted their activities and strategies over time to increase their resilience. After examining recent drought episodes from an agroclimatic perspective, information from an online survey was combined with evidence from semi-structured interviews with farmers to assess: drought risk perceptions, impacts of past drought events, management strategies at different scales (regional to farm level) and responses to future risks. Interviews with the water regulatory agency were also conducted to explore their attitudes and decision-making processes during drought events. The results highlight how agricultural drought management strategies evolve over time, including how specific aspects have helped to reduce future drought risks. The importance of adopting a vertically integrated drought management approach in the farming sector coupled with a better understanding of past drought impacts and management options is shown to be crucial for improving decision-making during future drought events

Investigation of the use of microwave image line integrated circuits for use in radiometers and other microwave devices in X-band and above

Program results are described in which the use of a/high permittivity rectangular dielectric image waveguide has been investigated for use in microwave and millimeter wavelength circuits. Launchers from rectangular metal waveguide to image waveguide are described. Theoretical and experimental evaluations of the radiation from curved image waveguides are given. Measurements of attenuation due to conductor and dielectric losses, adhesives, and gaps between the dielectric waveguide and the image plane are included. Various passive components are described and evaluations given. Investigations of various techniques for fabrication of image waveguide circuits using ceramic waveguides are also presented. Program results support the evaluation of the image line approach as an advantageous method for realizing low loss integrated electronic circuits for X-band and above

Depression and Contributors to Vocational Satisfaction in Roman Catholic Secular Clergy

A nationally selected, random sample of Roman Catholic secular (i.e., diocesan) priests was examined using the Center for Epidemiological Studies-Depression scale and an instrument developed for this study to assess contributors to priests’ vocational satisfaction. In addition, a self-report inventory gathered information regarding participants’ demographics as well as four categories of predictor variables (i.e., overall level of vocational satisfaction, social support, spiritual activities, physical environment). The study yielded a response rate of 45%. Secular clergy reported rates of depression approximately seven times greater than are found in the general population, and also indicated that the recent sexual abuse scandal in the Roman Catholic church had negatively affected their mood. Priests’ engagement in sacramental activities contributed greatly to their vocational satisfaction, and low levels of vocational satisfaction were found to be most predictive of depression. Factors comprising priests’ vocational satisfaction were External Manifestations (e.g., preaching, teaching), Internal Manifestations (e.g., prayer life, affirmation of God’s call), and Social Manifestations (e.g., relationships with parishioners, appreciation from others)

Assessment of Neuropsychological Trajectories in Longitudinal Population-Based Studies of Children

This paper provides a strategy for the assessment of brain function in longitudinal cohort studies of children. The proposed strategy invokes both domain-specific and omnibus intelligence test approaches. In order to minimise testing burden and practice effects, the cohort is divided into four groups with one-quarter tested at 6-monthly intervals in the 0–2-year age range (at ages 6 months, 1.0, 1.5 and 2.0 years) and at annual intervals from ages 3–20 (one-quarter of the children at age 3, another at age 4, etc). This strategy allows investigation of cognitive development and of the relationship between environmental influences and development at each age. It also allows introduction of new domains of function when age-appropriate. As far as possible, tests are used that will provide a rich source of both longitudinal and cross-sectional data. The testing strategy allows the introduction of novel tests and new domains as well as piloting of tests when the test burden is relatively light. In addition to the recommended tests for each age and domain, alternative tests are described. Assessment methodology and knowledge about child cognitive development will change over the next 20 years, and strategies are suggested for altering the proposed test schedule as appropriate